MRI Strategy

On-demand Translational Imaging & AI/ML-driven data analysis consulting and R&D for CROs, Pharma Partners, and Biotech

About

On-Demand Translational Imaging Expertise for CROs, Biotechs, and Pharma Partners with 10+ years of experience bridging preclinical models and clinical impact.

Specialized in end-to-end imaging workflows—from ex-vivo, in-vitro, and in vivo disease models to AI powered high field MRI (7 to 21.1T), multimodal image analysis, omics integration, and cloud-based pipelines.

Imaging driven product design and delivering scientifically aligned outcomes tailored to your project goals.

✔️ CONTACT
Dr. Shinho Cho
MRI Scientist & Imaging Consultant
📧 scho@MRIstrategy.com

Services

✔️ Biomarker Discovery & Validation
End-to-end support from target identification through validation to Phase I–III

✔️ CNS Disease Model Preclinical Study Design & Execution
Expertise in designing and running translational studies for neurological drug development

✔️ Imaging Protocol Development (MRI)
GLP-compliant preclinical and clinical MRI sequence/protocol design

✔️ AI/ML-based Image Analysis & Pipeline Automation
From data curation to quantitative endpoint extraction

✔️ Multimodal & Omics Data Integration
Fusion of MRI, PET/SPECT, CT, microscopy, behavioral, and multi-omics datasets

✔️ Cloud-Based Analytics Pipelines Development
Secure, scalable deployments with DICOM interoperability

✔️ Imaging-Driven Product Design
Conceptualization and prototyping of diagnostic devices and software

✔️ Imaging Core Lab & Quantitative Review
Blinded adjudication, QA/QC for centralized readouts

✔️ Regulatory & Compliance Consulting
Guidance for IACUC/IRB, GLP/GMP/FDA/EMA standards

✔️ Scientific Writing & Communication
Grant proposals, regulatory dossiers, manuscripts, and technical presentations

 Prostate Cancer Imaging–Omics — Cloud-Based Biomarker Discovery Pipeline (1/5)


Developed a cloud-native, multimodal imaging-omics pipeline using Flywheel.io to support biomarker discovery in prostate cancer. Integrated MRI and omics datasets at scale, enabling automated data curation and machine learning–driven analysis.

✔️Achieved biomarker identification performance exceeding 50% sensitivity and specificity, supporting translational research applications. 

Parkinson’s Circuit Mapping — DBS-fMRI Integration & Surgical Guidance (2/5)


Led translational imaging studies combining deep brain stimulation (DBS) and fMRI in Parkinson’s patients and large-animal models. Designed MRI-guided neurosurgical planning for DBS electrode placement. 

✔️Enhanced stimulation-specific network mapping. Improved DBS programming accuracy by 25% and reduced surgical planning time by 40%.

Early Alzheimer's Detection — High-Field Preclinical MRI Optimization (3/5)


Optimized Bruker MRI protocols across 7-9.4 Tesla systems for TgF344-AD rodents to detect early structural and functional biomarkers of Alzheimer’s disease. Custom-tailored parameters, coil designs, and artifact suppression strategies enhanced SNR and cross-platform reproducibility. 

✔️The finalized protocol is used in early-phase biomarker discovery and therapeutic trials.

Neuropharmacology & Imaging Agents — In Vivo PK/PD & Contrast Validation (4/5)


Performed pharmacodynamic mapping of acute morphine exposure using rodent MRI (9.4 T), identifying CNS alterations. Assessed biodistribution and CNS penetration of Feraheme (iron-based agent) and validated a manganese-based contrast agent with 50% signal enhancement (a.k.a MEMRI).

✔️Demonstrated translational potential for functional imaging in neuropharmacology.

Gene-to-Connectome Imaging — GLT-1 Functional & Structural MRI Phenotyping (5/5)


Used diffusion and resting-state MRI to characterize brain-wide alterations in GLT-1 gene-mutant rodents versus wild-type (21.1 Tesla - world's unique MRI). Tractography and connectivity analyses revealed distinct network disruptions linked to astrocytic glutamate transport. 

✔️Findings provide foundational imaging-based evidence for gene therapy strategies targeting GLT-1 dysregulation.

Your Project Will Be Here.


I commit to excellence, integrity, and clear communication.
You can expect high-quality results, strict timelines, and trust-based collaboration.

Let’s build something remarkable — together.

Dr. Shinho Cho
MRI Scientist & Imaging Consultant
📧 scho@MRIstrategy.com
🔗 https://www.linkedin.com/in/shinho-cho-ph-d-0573b54b/

Our Partners

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Contact Info

Linkedin

https://www.linkedin.com/in/shinho-cho-ph-d-0573b54b/

Address

Tallahassee, FL 32317

Work Hours

Mon-Fri: 9am-5pm

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